A Computational Model of Epilepsy

Inspired and built the code from:

Izhikevich, E. M. (2003). Simple model of spiking neurons. IEEE Transactions on neural networks, 14(6), 1569-1572.

The Izhikevich Model

Pulse - Coupled Network:

• Every neuron is coupled with neurons above and below, first and last neurons are connected
• Random distribution of excitatory and inhibitory neurons

Possible Causes of Epilepsy:

1. Lower threshold for firing: regulated by I parameter in the Izhikevich model
2. Shorter refractory period: regulated by a parameter in the model
3. A high ratio of excitatory neurons to inhibitory neurons

This code was co-created with Christina Bruckmann & Jens Dudink.